प्राण्यांच्या मॉडेलमध्ये चिंता कमी करण्यासाठी मॅचा चहा पावडर आणि अर्क यांचे परिणाम शास्त्रज्ञांनी प्रथमच दाखवले आहेत. मॅचा हा चिंता कमी करण्यासाठी आणि मूड सुधारण्यासाठी एक सुरक्षित, नैसर्गिक पर्याय आहे.
मूड आणि चिंता disorders are becoming commonplace in our fast-paced and often stressful lives. चिंता disorders and fear has been linked to disturbance in dopaminergic and serotonergic systems in our brain. चिंता symptoms also increases risk of other medical disorders and affects overall wellbeing of a person. Anxiolytic (or antianxiety) agents like benzodiazepines and serotonin inhibitors are generally used for treatment as they reduce or inhibit चिंता. However, they have many side effects, sometimes even adverse, and they also increase dependency. Safer, natural alternative need to be developed for चिंता व्यवस्थापन.
जपानमध्ये, 'मॅचा' वेगवेगळ्या औषधी हेतूंसाठी बर्याच काळापासून वापरला जातो. मॅचा म्हणजे झाडाच्या झाडापासून नवीन पानांची बारीक ग्राउंड केलेली शक्ती कॅमेलिया सीनेन्सिस ज्याला फक्त सावलीत वाढू दिले जाते. मॅचा पावडर बनवण्यासाठी वापरली जाते मॅचा चहा by adding it directly to hot water. It is also used for adding flavour to food. Matcha चहा is different from regular green tea in its content mainly because of differences cultivation and processing. कॅमेलिया सीनेन्सिस वनस्पतीमध्ये L-theanine, epigallocatechin gallate (EGCG), कॅफीन, जीवनसत्त्वे आणि अमीनो ऍसिड भरपूर प्रमाणात असतात आणि अशा प्रकारे मॅचाचे सेवन केल्याने या बायोएक्टिव्ह पदार्थांशी संबंधित अनेक फायदे मिळतात. हे जपानमध्ये सामान्यतः उपचार, विश्रांती आणि त्वचेच्या स्थितीवर उपचार करण्यासाठी वापरले जाते. तथापि, वरील दाव्यांचे समर्थन करण्यासाठी अत्यंत मर्यादित वैज्ञानिक पुरावे उपलब्ध आहेत. तसेच, वर्तणुकीच्या पैलूंवर मॅचा पावडरचे परिणाम आजपर्यंत शोधले गेले नाहीत.
मध्ये प्रकाशित एक अभ्यास जर्नल ऑफ फंक्शनल फूड्स has investigated and demonstrated the effects of Matcha चहा powder, hot water extract and ethanol extract for प्रतिरोधकपणा activity in an animal model (here, mice). Researchers conducted an elevated plus maze (EPM) test in healthy animals. EPM involves use of an elevated plus-shaped platform which has two open arms and two closed arms with walls around it. It is a commonly used anxiety test in which animal subjects which are anxious try to stay on the safe area of the plus where they cannot fall off.
The animals were orally administered Matcha powder and extract or fractions dissolved in water. Results showed that the animals who had consumed Matcha had reduced चिंता. The strongest effect was seen in Matcha extract derived using 80% ethanol when compared to extract derived from hot water. This meant that poor water-solubility of Matcha has better प्रतिरोधकपणा effect than when it was easily water soluble. The ethanol extract was fractioned further into hexane soluble, ethyl acetate soluble and water-soluble fractions which exhibited similar results. Behavioural analysis showed that Matcha power and extract reduce चिंता by activating dopamine D1 and serotonin 5-HT1A receptors which are closely linked to anxious behaviour.
The current study conducted on mice demonstrates that Matcha चहा powder and extract have a positive calming effect and reduce anxiety by activating dopaminergic and serotonergic systems in the brain. Matcha is a safe and natural alternative for alleviating anxiety.
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{उद्धृत स्रोतांच्या सूचीमध्ये खाली दिलेल्या DOI लिंकवर क्लिक करून तुम्ही मूळ शोधनिबंध वाचू शकता}
स्त्रोत
Kurauchi, Y. et al. 2019. Anxiolytic activities of Matcha चहा powder, extracts, and fractions in mice: Contribution of dopamine D1 receptor- and serotonin 5-HT1A receptor-mediated mechanisms. Journal of Functional Foods. https://doi.org/10.1016/j.jff.2019.05.046
